CLINICAL CASE I - 3

No, it is not necessary to modify the interval because the patient did not have significant clinical exacerbations

No, the patient did not have significant clinical exacerbations but reducing intervals between infusion can increase the risk of side effects

Yes, the patient is not clinically stable, but since the side effects of reducing the infusion interval are unknown, close clinical and laboratory monitoring is necessary

Yes, the patient is not clinically stable, and there are no additional risk of side effects in case of reducing the interval between infusion