CLINICAL CASE I - 1

Failure to respond to non unconventional treatment

Inability to reduce immunosopressive therapy without clinical relapse or need for ongoing rescue therapy (e.g IVIG or PLEX)

Severe or intolerable adverse effects from immunosoppresive or symptomatic therapy

Comorbidity conditions restricting use of conventional therapy

Frequent myasthenic crisis even while on immunosoppressive and symptomatic therapy

All of the answers